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BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE

About

BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS).

BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE contains Bictegravir, Emtricitabine and Tenofovir as key ingredients. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction.

BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. If these side effects persist, please consult your doctor. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE should be taken as advised by your doctor.

BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE should be avoided if you are allergic to it. This medicine is contraindicated in patients with Hepatitis B infection and severe hepatic impairment. Before taking this medicine, inform your doctor if you have liver/kidney disease, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If you are pregnant and breastfeeding, let your doctor know before taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE should be used in children only if recommended by the doctor.

Uses of BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE

Treatment of Human Immunodeficiency Virus (HIV) Infection

Medicinal Benefits

BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE is a combination of Bictegravir, Emtricitabine and Tenofovir. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Directions for Use

Take BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE as advised by your doctor. It can be taken with or without food. Swallow as a whole with a glass of water. Do not chew, crush, or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE

  • Nausea
  • Abdominal pain
  • Vomiting
  • Joint ache
  • Fatigue
  • Loss of appetite
  • Myalgia
  • Skin rash
  • Diarrhoea
  • Headache
  • Dizziness

In-Depth Precautions and Warning

Drug Warnings

BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE should be avoided if you are allergic to it. This medicine is contraindicated in patients with severe hepatic impairment, hepatitis B infection and a combination of other HIV medicines. Inform your doctor about your medical history and the medicines you take to prevent possible interactions. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. If the patient develops any signs or symptoms of hepatitis, increased transaminase, rash, or hypersensitivity reactions, BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE should be discontinued immediately. This medicine may cause dizziness; hence, avoid driving or operating machines while taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE. Before taking this medicine, inform your doctor if you have liver/kidney diseases, hypersensitivity reactions, Stevens-Johnson syndrome, cirrhosis, or hepatic fibrosis. If pregnant and breastfeeding, inform your doctor before taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE should be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE treats the infection but does not cure or prevent it.

Drug Interactions

Drug-Drug Interactions: BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE may interact with contraceptives (ethyl estradiol, norethindrone), anti-viral drugs (adefovir dipivoxil, atazanavir, lamivudine), anti-Tb drug (rifampicin), ulcer medicine (sucralfate), antibiotics (azithromycin, clarithromycin, rifabutin), immunosuppressants (cyclosporine), anti-epileptics (phenobarbital or phenytoin), antacids, iron supplements and vitamins.

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have moderate to severe hepatic impairment, Stevens-Johnson syndrome, cirrhosis, hepatic fibrosis, and other skin disorders before starting treatment with BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE.

Drug-Drug Interactions Checker List:

  • ADEFOVIR
  • ATAZANAVIR
  • RIFAMPICIN
  • SUCRALFATE
  • CLARITHROMYCIN
  • CYCLOSPORIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid alcohol consumption while on treatment with BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE. Alcohol intake might increase the risk of stomach or intestine bleeding.

    • Safety Warning

      Pregnancy

      caution

      If you are pregnant or suspect you may be pregnant, inform your doctor before taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE. Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

    • Safety Warning

      Breast Feeding

      unsafe

      BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE is excreted in milk. If you have HIV or are taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE, you should not breastfeed your baby.

    • Safety Warning

      Driving

      unsafe

      Avoid driving vehicles or operating machines after taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE as it may cause fatigue.

    • Safety Warning

      Liver

      caution

      BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE can result in serious, sometimes fatal, liver damage. Inform your doctor if you have or have had a liver illness, particularly hepatitis B or C. Your doctor will most likely advise you not to take BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE.

    • Safety Warning

      Kidney

      caution

      Before using BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE, inform your doctor if you have or have ever had kidney disease, particularly if you are on dialysis treatment.

    • Safety Warning

      Children

      consult your doctor

      Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
    • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
    • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
    • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
    • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
    • Drink more fluids and avoid alcoholic beverages to prevent dehydration.  
    • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
    • Avoid sharing used needles, other injection or drug equipment.

    Special Advise

    • Get an HIV test done at least every three months.
    • BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE should be carefully monitored throughout the treatment.
    • Periodic liver function and CBC tests are recommended while taking BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE.

    Patients Concern

    Disease/Condition Glossary

    HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.

    FAQs

    BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE is used to treat HIV Infection.

    BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction.

    No, completing the treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.

    BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE doesnot cure HIV infection. However, it helps to control the disease and prevent opportunistic infections. BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE is used in combination with other anti-retroviral medicines.

    Available Medicines for

    BICTEGRAVIR+EMTRICITABINE+TENOFOVIR ALAFENAMIDE

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